sb 4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7799	BMP signaling agonist sb4	SB 4	TGF-beta/Smad
	BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)		TGF-beta/Smad
T1726	SB-431542	SB 431542	ALK , TGF-beta/Smad
	SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiatio...		ALK , TGF-beta/Smad
T23321	SB 328437	(S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate,ZINC29222893	CCR
	SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).		CCR
T6658	SB-408124		OX Receptor
	SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.		OX Receptor
T6659	SB 415286	SB415286	Apoptosis , GSK-3
	SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.		Apoptosis , GSK-3
T2278	Piboserod	SB-207266	5-HT Receptor
	Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist.		5-HT Receptor
T1764	Adezmapimod	PB 203580,RWJ 64809,SB203580	Mitophagy , p38 MAPK , Autophagy
	Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive. Adezmapimod possesses autophagy and mitochondrial autophagy activating activity. Adezmapimod displays more than 100...		Mitophagy , p38 MAPK , Autophagy
T38602	(E/Z)-Eltrombopag 13C4	(E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4
	(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead...
T6644	Rolipram	SB 95952,ZK 62711,(R,S)-Rolipram	HIV Protease , Antibacterial , PDE
	Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.		HIV Protease , Antibacterial , PDE
T77426	Pascolizumab	SB-240683	IL Receptor
	Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.		IL Receptor
T6445	Cilomilast	SB-207499,Ariflo	PDE
	Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.		PDE
T4674	SB297006	SB 297006	CCR
	SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...		CCR
T124135	Antibiotic SB 202742
	Antibiotic SB 202742 is a useful organic compound for research related to life sciences. The catalog number is T124135 and the CAS number is 83173-24-4.
T36376	SB-612111
	SB-612111 is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6...